Mean (SD) values of lung function indices in 171 patients with PPH and 64 controls
| PPH | Controls | Mean difference | ||
|---|---|---|---|---|
| (n=171) | (n=64) | (95% CI) | p value* | |
| CI = confidence interval; TLC = total lung capacity; RV = residual volume; Rtot = airway resistance; VC = vital capacity; FEV1 = forced expiratory volume in 1 second; PEF = peak expiratory flow; MEF75, 50, 25 = maximal expiratory flow at 25%, 50%, and 75% of exhaled VC, respectively. *Student's t test. | ||||
| TLC (% predicted) | 98 (12) | 102 (17) | −4 (−7.9 to −0.1) | 0.046 |
| RV (% predicted) | 118 (24) | 109 (27) | 9 (1.9 to 16.1) | <0.001 |
| RV/TLC (% predicted) | 117 (27) | 97 (29) | 20 (12.3 to 27.8) | <0.001 |
| Rtot (% of upper limit) | 98 (42) | 91 (42) | 7 (−5.1 to 19.1) | 0.26 |
| VC (% predicted) | 91 (16) | 102 (10) | −11 (15.2 to −6.8) | <0.001 |
| FEV1 (% predicted) | 83 (15) | 106 (9) | −23 (−26.9 to −19.1) | <0.001 |
| FEV1/VC (%) | 76 (8) | 84 (5) | −8 (10.09 to −5.90) | <0.001 |
| PEF (% predicted) | 85 (21) | 98 (12) | −13 (−18.5 to −7.6) | <0.001 |
| MEF75 (% predicted) | 82 (24) | 103 (13) | −21 (−27.2 to −14.8) | <0.001 |
| MEF50 (% predicted) | 66 (24) | 101 (19) | −35 (−41.5 to −28.5) | <0.001 |
| MEF25 (% predicted) | 46 (23) | 82 (22) | −36 (−42.5 to −29.5) | <0.001 |