Variable2-151 | No wheezing (n=455) | Current wheezing (n=73) | Frequent wheezing (n=33) | Persistent wheezing (n=35) |
Malaria | ||||
Cord blood parasite (any) | 2.3% | 9.6%2-150 | 12%2-150 | 14%2-150 |
Intervention group | ||||
Deltaprim | 50% | 47% | 51.5% | 40% |
Iron | 39% | 40% | 36% | 40% |
Clinical malaria episodes | ||||
1–2 | 30% | 30% | 36% | 23% |
>2 | 39% | 40% | 36% | 40% |
LRTI before 18 months | ||||
>1 episode | 54% | 67%2-150 | 70%2-150 | 80%2-150 |
No of episodes | 0.80 | 1.562-150 | 1.872-150 | 2.02-150 |
Total IgE (kU/ml) | ||||
Cord blood >1.9 kU/l | 19% | 5.9%2-150 | 4.5% | 10% |
Mean at 18 months2-160 | 150 | 124 | 136 | 125 |
Parity | ||||
First | 27% | 27% | 37% | 20% |
Four or more | 34% | 27% | 20% | 34% |
Maternal | ||||
Mean age | 26.2 | 25.8 | 24.4 | 27.1 |
Asthma | 1.3% | 10%2-150 | 9.4% | 21%2-150 |
Atopy | 63% | 64% | 80% | 57% |
IgE >1000 kU/l | 62% | 60% | 57% | 61% |
IgE >2000 kU/l | 32.5% | 34% | 38% | 25% |
Environment2-152 | ||||
Fire, no ventilation | 22% | 23% | 21% | 28% |
No of people | 6.2 | 6.5 | 6.6 | 6.92-150 |
Breastfed | 97% | 93% | 92% | 97% |
Fel d I in dust (μg/g)2-160 | 0.35 | 0.57 | 0.12 | 0.84 |
Der pI in dust (μg/g)2-160 | 2.28 | 1.16 | 1.55 | 1.13 |
↵2-150 p<0.05 compared with no wheeze at 4 years (or never wheeze in the case of persistent wheeze, which figures were very similar to no wheezers at 4 years).
↵2-151 Definition in table 1.
↵2-152 Only included variables with p<0.25 in the crude association with wheezing, among the following variables: earth floor, humidity, electricity, number of rooms, density, occupation, parental smoking, animals. The minimum number of observations in a cell for allergens in dust was 8.
↵2-160 Geometric mean.