Table 1

Mean (SD) values (n=8) for mean arterial pressure (MAP), heart rate (HR), QTc interval, forearm vascular resistance (FVR), and serum potassium levels (K+) at baseline (t=0) and at the end of the experiment (t=60)

MAP (mm Hg)HR (bpm)QTc (ms)FVR (mmHg/%FBF)K+(mmol/l)
t=0t=60t=0t=60t=0t=60t=0t=60t=0t=60
NP81.7 (6.9)82.4 (9.3)69.0 (8.1)64.8 (11.5)390 (20)395 (12)29.3 (14.2)28.3 (13.6)4.22 (0.14)4.10 (0.37)
HP82.5 (7.2)82.5 (7.8)65.0 (9.4)70.9 (10.9)1-160 389 (15)397 (16)26.2 (11.4)23.9 (13.6)3.99 (0.21)4.01 (0.15)
NS81.6 (8.1)83.5 (7.9)65.1 (8.4)66.8 (13.3)393 (14)398 (12)25.0 (7.4)21.1 (8.3)4.06 (0.28)4.02 (0.35)
HS81.8 (3.9)82.9 (8.6)62.4 (8.7)76.3 (9.2)*** 384 (18)409 (23)1-150 30.9 (9.5)21.9 (8.9)1-160 4.08 (0.26)3.89 (0.17)
p value0.857 <0.0010.0370.0340.495
  • NP = normoxia + placebo; HP = hypoxia + placebo; NS = normoxia + salbutamol; HS = hypoxia + salbutamol.

  • Significant differences from NP as percentage change from t=0 value:

  • 1-150 p<0.05;

  • 1-160 p<0.01;*** p<0.001.