Table 2

Relation of ECRHS “slope” to body mass index or weight, with three methods of adjustment for baseline FEV₁, estimated by random effects meta-analysis of regression coefficients across 34 centres. All analyses adjusted for independent variables as described in text

	Men (n=5899)				Women (n=5354)
Adjustment for baseline FEV₁	Meta-analysis regression coefficient	95% CI	p value for regression coefficient	p value for heterogeneity	Meta-analysis regression coefficient	95% CI	p value for regression coefficient	p value for heterogeneity	p value for interaction of sex and BMI
*Internally standardised difference between FEV₁ and value predicted for sex, age and height, divided by residual standard deviation.
†Regression coefficient on weight with adjustment for FEV₁, height, and height².
Standardised difference*	−0.027	−0044 to −0.010	0.002	0.10	−0.014	−0.033 to 0.005	0.14	0.011	0.41

FEV₁/height²	−0.027	−0044 to −0.010	0.002	0.10	−0.005	−0.033 to 0.004	0.13	0.011	0.46

Regression method†	−0.009	−0.014 to −0.003	0.003	0.09	−0.002	−0.013 to 0.002	0.13	0.005	0.60