Baseline comparison of lung function and respiratory muscle assessment
| Normal subjects (n=9) | COPD (n=8) | Neuromuscular weakness | |||||
|---|---|---|---|---|---|---|---|
| Without scoliosis (n=8) | With scoliosis (n=4) | ||||||
| Age (years) | 27 (17–71) | 65 (52–74) | 63 (27–73) | 57 (44–66) | |||
| Sex | 4M, 5F | 3M, 5F | 8M | 3M, 1F | |||
| FEV1 (l) | 3.8 (1.7–4.2) | 0.95 (0.35–1.1) | 0.73 (0.48–1.8) | 0.8 (0.65–1.25) | |||
| FEV (% pred) | 98 (88.3–120.1) | 37 (13.4–44.2) | 19 (13.6–43.9) | 33 (28.4–40.4) | |||
| FVC (l) | 4.6 (2.1–5.9) | 1.8 (0.77–2.75) | 0.83 (0.55–1.57) | 1.5 (0.7–1.75) | |||
| FVC (% pred) | 100 (78.3–120.8) | 66 (24.5–84.9) | 18 (13–42.0) | 35 (15–42.9) | |||
| PEFR (l/min) | 444 (410–633) | 212 (110–270) | 123 (68–150) | 225 (220–240) | |||
| PEFR (% pred) | 103 (86.9–140) | 51 (24.9–66.7) | 24 (13.1–31.9) | 47 (45.7–66.7) | |||
| Pimax (cm H2O) | 99 (59–137) | 37 (18–91) | 15 (11–22) | 37 (30–49) | |||
| Pimax (% pred) | 115 (87–151) | 44 (18.5–93.3) | 14 (11.9–24.9) | 41 (37.6–50.7) | |||
| Pemax (cm H2O) | 126 (104–239) | 84 (52–167) | 22 (16–35) | 51 (17–62) | |||
| Pemax (% pred) | 118 (83–228) | 94 (74.7–194.3) | 19 (11.7–27.6) | 42 (36.4–67.3) | |||
| MVV (l/min) | 128 (75–195) | 33 (19–60) | 26 (16–35) | 33 (21–44) | |||
| MVV (% pred) | 107 (71–115) | 32 (16.7–66.1) | 17 (11.1–27.8) | 24 (17.0–33.8) | |||
Data are expressed as median (range).
FEV1 = forced expiratory volume in one second; FVC = forced vital capacity; PEFR = peak expiratory flow rate; Pimax, Pemax = maximum inspiratory and expiratory pressure; MVV = maximum voluntary ventilation.