Table 2

Presence of systemic markers of inflammation in patients with stable COPD compared with control subjects

	Healthy controls (n=23)	Stable COPD (n=55)	p Value^2-150
Leucocyte count (10⁹/l)	4.8 (3.5–8.3)^2-151	7.2 (4.7–16.4)	<0.005
CRP (μg/ml)	4.1 (0.6–75.0)	11.8 (1.1–75.0)	<0.005
LBP (μg/ml)	27.9 (14.1–71.5)	45.6 (8.1–200.0)	<0.005
sTNF-R55 (ng/ml)	0.56 (0.36–0.90)	0.66 (0.37–2.44)	<0.05
sTNF-R75 (ng/ml)	1.59 (0.96–2.87)	1.72 (0.81–4.66)	NS
sIL-1RII (ng/ml)	4.63 (3.80–5.93)	4.53 (2.09–7.60)	NS

Data are median (range).
↵2-150 Mann-Whitney U test.
↵2-151 Value for 19 healthy controls.
CRP = C reactive protein; LBP = lipopolysaccharide binding protein; sTNF-R = soluble tumour necrosis factor receptor; sIL-1RII = soluble interleukin 1 receptor II; NS = non-significant.