Mean (SD) values of the haemodynamic parameters at baseline and after 1 year NMV in patients with thoracic restriction (group A) and patients with COPD (group B)
| Group A | Group B | ||||||
|---|---|---|---|---|---|---|---|
| Before exercise | p value | Max | Before exercise | p value | Max | ||
| Baseline | |||||||
| PAPmean (mm Hg) | 33.2 (10.0) | 3-169 | 55.1 (14.4) | 25.3 (6.0) | 3-169 | 44.8 (14.1) | |
| PCW (mm Hg) | 9.0 (5.0) | 3-169 | 16.4 (5.5) | 8.7 (3.2) | 3-169 | 15.5 (4.6) | |
| PVRI (dyn/s/cm5/m2) | 606 (200) | 654 (172) | 410 (127) | 3-159 | 474 (143) | ||
| After 1 year NMV | |||||||
| PAPmean (mm Hg) | 24.8 (6.2) | 3-169 | 46.9 (13.9) | 27.5 (6.0) | 3-169 | 47.8 (10.2) | |
| PCW (mm Hg) | 9.2 (3.4) | 3-169 | 16.4 (5.5) | 9.2 (2.5) | 3-169 | 16.5 (5.0) | |
| PVRI (dyn/s/cm5/m2) | 432 (158) | 3-159 | 508 (169) | 408 (92) | 3-159 | 471 (111) | |
| Mean change (95% CI) | |||||||
| PAPmean (mm Hg) | –8.5 (–12.6 to –4.3)3-160 | –8.2 (–14.6 to –1.7)3-150 | 2.2 (–0.3 to 4.8) | 3.0 (–2.6 to 8.6) | |||
| PCW (mm Hg) | 0.2 (–2.3 to 2.7) | –0.1 (–4.6 to 4.3) | 0.5 (–0.9 to 2.0) | 1.0 (–0.8 to 2.8) | |||
| PVRI (dyn/s/cm5/m2) | –174 (–288 to –61)3-160 | –146 (–239 to –53)3-150 | –2 (–99 to 95) | –3 (–46 to 40) | |||
PAP = pulmonary arterial pressure; PCW = pulmonary wedge pressure; PVRI = pulmonary vascular resistance index.
↵3-150 Mean change in haemodynamic parameters (95% confidence interval, CI) from baseline to 1 year NMV (3-150p<0.05,
↵3-160 p<0.01, Wilcoxon test).
↵3-159 Comparison of the values before and at the end of maximal load (max) (3-159p<0.05,
↵3-169 p<0.001, Wilcoxon test).