Characteristics of 590 participants in the Lung Health Study group divided into those with no decline and those with a rapid decline in lung function
|
No decline (n=306) |
Rapid decline (n=284) | p value | |
| Age | 47.6 (0.4) | 49.6 (0.4) | 0.0004 |
| Sex (% men) | 67% | 58% | 0.04 |
| Rate of decline (ml/year) | 14.9 (2.0) | –153.6 (2.1) | <0.0001 |
| Pack-years | 38.4 (1.1) | 42.9 (1.1) | 0.003 |
| Baseline FEV1 (% predicted) | 75.7 (0.5) | 72.7 (0.5) | <0.0001 |
| Methacholine response (%) (O'Connor slope1-150) | –7.8 (1.5) | –23.0 (1.5) | <0.0001 |
Values are mean (SE).
FEV1 = forced expiratory volume in 1 second.
↵1-150 Percentage decline in FEV1 per final cumulative dose of methacholine administered.33