Mean (SD) data for the study subjects
|
Healthy volunteers (n=36) |
Emphysema patients (n=32) | |
| Age (years) | 33 (9) | 62 (9) |
| M:F | 18:18 | 16:16 |
| Smoking history | 5 current smokers 31 non-smokers | 15 current smokers 17 ex-smokers |
| Mean Tco (day 1) | 9.92 (2.05) | 3.66 (1.43) |
| Mean Kco (day 1) | 1.61 (0.19) | 0.78 (0.23) |
| % Predicted FEV1 (day 1) | 102 (11.8) | 48 (23.3) |
| % Predicted VC (day 1) | 103 (7.7) | 82 (20.9) |
| % Predicted Tco (day 1) | 98 (13.8) | 48 (16.0) |
| % Predicted Kco (day 1) | 99 (13.2) | 55 (17.8) |
Tco = carbon monoxide transfer factor; Kco = carbon monoxide transfer coefficient; FEV1 = forced expiratory volume in one second; VC = vital capacity.