Patient characteristics (n=106)
| Evaluated parameter | Number (%) | Mean (SD) | Range |
| Age (years) | 61 (11) | 19–81 | |
| Male/female | 65/41 | ||
| Diagnosis based on histology | 45 (42) | ||
| Open lung biopsy | 32 (30) | ||
| Necropsy | 6 (6) | ||
| Transbronchial biopsy | 7 (7) | ||
| Diagnosis based on HRCT findings alone | 61 (57) | ||
| Smoking history | 106 (100) | ||
| Never smokers | 37 (35) | ||
| Ex-smokers | 69 (65) | ||
| Follow up (months)1-151 | 15.0 | 0.5–56.9 | |
| Pulmonary function | 105 (99) | ||
| FEV1 (l) | 2.0 (0.6) | 1.0–3.8 | |
| FEV1 (% predicted) | 76 (22) | 31–133 | |
| FVC (l) | 2.5 (0.9) | 1.1–5.7 | |
| FVC (% predicted) | 76 (24) | 28–141 | |
| TLC (l) | 4.1 (1.2) | 1.8–8.7 | |
| TLC (% predicted) | 74 (21) | 29–133 | |
| Tlco (mmol/kPa/min) | 4.0 (1.6) | 1.0–9.7 | |
| Tlco (% predicted) | 48 (16) | 12–102 | |
| Kco (mmol/kPa/min/l) | 1.1 (0.4) | 0.4–2.1 | |
| Kco (% predicted) | 79 (24) | 34–146 | |
| Blood gas analysis | 102 (96) | ||
| Pao 2 (kPa) | 8.7 (1.6) | 4.9–12.1 | |
| Paco 2 (kPa) | 4.9 (0.6) | 2.8–6.8 | |
| Sao 2 (%) | 94 (4) | 73–99 | |
| BAL differential cell counts | 79 (75) | ||
| Macrophages (%)1-151 | 58 | 12–87 | |
| Neutrophils (%)1-151 | 15 | 1–84 | |
| Lymphocytes (%)1-151 | 6 | 0–59 | |
| Eosinophils (%)1-151 | 3 | 0–43 | |
| HRCT score | 71 (67) | ||
| HRCT fibrosis score | 2.0 (0.7) | 0.5–3.5 | |
| HRCT ground glass score | 3.1 (1.2) | 0.8–5.0 |
↵1-151 Median values are given for non-normally distributed data.
FEV1 = forced expiratory volume in one second; FVC = forced vital capacity; TLC = total lung capacity; Tlco = carbon monoxide lung transfer factor; Kco = carbon monoxide transfer coefficient; Pao 2 = arterial oxygen tension; Paco 2 = arterial carbon dioxide tension; Sao 2 = oxygen saturation; BAL = bronchoalvolar lavage; HRCT = high resolution CT.