Table 1

Clinical and physiological characteristics of the subjects studied

Age Sex Atopy IgE (IU/ml) FEV1 (% pred) PC20(mg/ml) Treatment
Controls
124MY 700111.1>32None
220FN  17118.3>32None
322FY  30119.8>32None
419FN<10100.0>32None
523MY<1097.8>32None
622FY  22116.0>32None
719FY<1090.5>32None
835FN<10105.7>32None
921MY 175136.3>32None
1022FY  46105.6>32None
Mean22.7110.1
SE1.54.2
Geometric mean>32
Non-steroid treated asthmatics
121FY NA122.3 3.85S
219FY 442100.3 6.92S
321FY 22977.4 3.49S
420FY 72799.0 0.59S
520FY 26691.3 0.29S
621FY 275131.4 2.21S
723MY1230105.9 0.32S
Mean20.7103.9
SE0.56.9
Geometric mean 1.41
Steroid treated asthmatics
121MY 182100.5 3.35P(10), S
225MY 26769.8  1.78P(10), S
341FY<1050.2<0.03BDP (1500), S
420MY  72109.217.59P(10), S
521FY NA97.9 7.5P(10), S
621FY  6285.4 0.71P(10), S
755FY  2639.7 NABDP (2000), P(10), T, S
833MY NA22.9 NAP(10), S
Mean29.671.9
SE4.511.2
Geometric mean<1.60
  • FEV1 = forced expiratory volume in one second; PC20 = provocative concentration of histamine producing a 20% fall in FEV1; S = salbutamol; P = prednisolone (daily dose in mg); BDP = beclomethasone dipropionate (daily dose in μg); T = theophylline; NA= not available.