Mean (SE) AQLQ scores by ethnic group at the start of the prospective study
| Study protocol | AQLQ start | Within group (start vs end) difference | Between group (active vs control) difference | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Mean (95% CI) | p value | Mean (95% CI) | p value | ||||||
| All subjects (n = 522) | |||||||||
| Overall | Control | 6.02 (0.06) | –0.12 (–0.17 to –0.07) | <0.001 | 0.22 (0.15 to 0.29) | <0.001 | |||
| Active | 6.01 (0.05) | 0.10 ( 0.05 to 0.15) | <0.001 | ||||||
| Activity | Control | 6.13 (0.06) | –0.15 (–0.21 to –0.09) | <0.001 | 0.18 (0.09 to 0.26) | <0.001 | |||
| Active | 6.21 (0.05) | 0.03 (–0.03 to 0.08) | 0.348 | ||||||
| Symptom | Control | 6.01 (0.06) | –0.12 (–0.17 to –0.06) | <0.001 | 0.25 (0.17 to 0.33) | <0.001 | |||
| Active | 5.95 (0.06) | 0.13 ( 0.07 to 0.19) | <0.001 | ||||||
| Emotional | Control | 5.77 (0.08) | –0.03 (–0.07 to 0.02) | 0.313 | 0.24 (0.15 to 0.32) | <0.001 | |||
| Active | 5.65 (0.08) | 0.21 ( 0.15 to 0.28) | <0.001 | ||||||
| Exposure | Control | 6.08 (0.06) | –0.17 (–0.23 to 0.11) | <0.001 | 0.22 (0.14 to 0.29) | <0.001 | |||
| Active | 6.09 (0.05) | 0.05 ( 0.00 to 0.10) | 0.072 | ||||||
| White Europeans (n = 242) | |||||||||
| Overall | Control | 6.04 (0.09) | –0.08 (–0.15 to –0.02) | 0.016 | 0.17 (0.07 to 0.26) | 0.001 | |||
| Active | 6.03 (0.08) | 0.08 ( 0.02 to 0.15) | 0.015 | ||||||
| Activity | Control | 6.21 (0.08) | –0.11 (–0.19 to –0.02) | 0.014 | 0.13 (0.01 to 0.24) | 0.028 | |||
| Active | 6.20 (0.07) | 0.02 (–0.06 to 0.09) | 0.628 | ||||||
| Symptom | Control | 5.97 (0.10) | –0.08 (–0.16 to 0.00) | 0.060 | 0.19 (0.08 to 0.30) | 0.001 | |||
| Active | 5.96 (0.09) | 0.11 ( 0.03 to 0.19) | 0.007 | ||||||
| Emotional | Control | 5.83 (0.11) | 0.01 (–0.05 to 0.08) | 0.746 | 0.14 (0.04 to 0.25) | 0.009 | |||
| Active | 5.83 (0.11) | 0.15 ( 0.07 to 0.24) | 0.001 | ||||||
| Exposure | Control | 6.08 (0.09) | –0.17 (–0.27 to –0.07) | 0.001 | 0.23 (0.11 to 0.34) | <0.001 | |||
| Active | 6.03 (0.08) | 0.06 (–0.01 to 0.13) | 0.067 | ||||||
| Indian subcontinent (n = 280) | |||||||||
| Overall | Control | 6.01 (0.07) | –0.15 (–0.21 to –0.09) | <0.001 | 0.26 (0.17 to 0.36) | <0.001 | |||
| Active | 6.00 (0.06) | 0.11 ( 0.00 to 0.19) | 0.003 | ||||||
| Activity | Control | 6.07 (0.07) | –0.18 (–0.26 to –0.10) | <0.001 | 0.22 (0.10 to 0.33) | <0.001 | |||
| Active | 6.23 (0.06) | 0.03 (–0.05 to 0.12) | 0.417 | ||||||
| Symptom | Control | 6.05 (0.08) | –0.15 (–0.23 to –0.07) | 0.001 | 0.30 ( 0.18 to 0.42) | <0.001 | |||
| Active | 5.95 (0.07) | 0.15 ( 0.06 to 0.24) | 0.001 | ||||||
| Emotional | Control | 5.71 (0.11) | –0.06 (–0.13 to 0.02) | 0.132 | 0.32 (0.06 to 0.44) | <0.001 | |||
| Active | 5.49 (0.11) | 0.26 ( 0.16 to 0.37) | <0.001 | ||||||
| Exposure | Control | 6.09 (0.08) | –0.18 (–0.25 to –0.10) | <0.001 | 0.21 (0.10 to 0.31) | <0.001 | |||
| Active | 6.13 (0.07) | 0.03 (–0.04 to 0.10) | 0.423 | ||||||
Range from 1 (minimum) = severe limitation or most of the time to 7 (maximum) = no limitation or none of the time. Within group (start versus end) and between group (active versus control) analysis shown with mean (SE) differences and 95% CI. Statistically significant where p<0.05.