No. (%) of subjects with clinical outcome | Actual total no.of events | ||||||
---|---|---|---|---|---|---|---|
Active | Control | OR (95% CI) | p value | Active | Control | p value | |
All subjects | n = 304 | n = 289 | n=304 | n=289 | |||
Admissions | 10 (3.3) | 18 (6.2) | 0.51 (0.22 to 1.14) | 0.1355 | 10 | 30 | 0.0246 |
A&E | 8 (2.6) | 12 (4.2) | 0.63 (0.23 to 1.68) | 0.4251 | 11 | 14 | 0.5657 |
DDS/GP | 5 (1.6) | 12 (4.2) | 0.39 (0.12 to 1.20) | 0.1135 | 8 | 19 | 0.1046 |
GP consults | 127 (41.8) | 167 (57.8) | 0.52 (0.37 to 0.74) | 0.0001 | 341 | 476 | 0.0044 |
Steroids | 54 (17.8) | 69 (23.9) | 0.69 (0.45 to 1.05) | 0.0831 | 92 | 177 | 0.0058 |
Antibiotics | 106 (34.9) | 148 (51.2) | 0.51 (0.36 to 0.72) | <0.0001 | 220 | 340 | 0.0005 |
White Europeans | n = 153 | n = 146 | n = 153 | n = 146 | |||
Admissions | 2 (1.3) | 9 (6.2) | 0.20 (0.03 to 1.01) | 0.0545 | 2 | 19 | 0.0309 |
A&E | 2 (1.3) | 10 (6.8) | 0.18 (0.03 to 0.90) | 0.0319 | 2 | 12 | 0.0133 |
DDS/GP | 1 (0.7) | 8 (5.5) | 0.11 (0.01 to 0.91) | 0.0355 | 3 | 14 | 0.0651 |
GP consults | 51 (33.3) | 87 (59.6) | 0.34 (0.21 to 0.56) | <0.0001 | 123 | 264 | 0.0002 |
Steroids | 24 (15.7) | 40 (27.4) | 0.49 (0.27 to 0.90) | 0.0199 | 34 | 105 | 0.0007 |
Antibiotics | 35 (22.9) | 71 (48.6) | 0.31 (0.18 to 0.53) | <0.0001 | 57 | 177 | <0.0001 |
Indian subcontinent | n = 151 | n = 143 | n = 151 | n = 143 | |||
Admissions | 8 (5.3) | 9 (6.3) | 0.83 (0.28 to 2.44) | 0.9081 | 8 | 11 | 0.4516 |
A&E | 6 (4.0) | 2 (1.4) | 2.92 (0.52 to 21.2) | 0.3184 | 9 | 2 | 0.1591 |
DDS/GP | 4 (2.6) | 4 (2.8) | 0.95 (0.19 to 4.60) | 1 | 5 | 5 | 0.9414 |
GP consults | 76 (50.3) | 80 (55.9) | 0.80 (0.49 to 1.30) | 0.3971 | 218 | 212 | 0.8782 |
Steroids | 30 (19.9) | 29 (20.3) | 0.97 (0.53 to 1.79) | 1 | 58 | 72 | 0.9458 |
Antibiotics | 71 (47.0) | 77 (53.8) | 0.76 (0.47 to 1.23) | 0.2922 | 163 | 163 | 0.7431 |
Number (%) of subjects analysed by χ2 with continuity correction or Fisher's exact test, reporting odds ratios and 95% CI. The total number of asthma events within each group categorised (0, 1, 2, 3, . . .) and analysed using Mantel-Haenszel test for linear association (χ2 for trend). p values <0.05 significant.