No. | Subgroups | |
Main reasons for ineligibility (n = 435) | ||
Logistical | ||
Followed at other centres Delay in referral or identification | 90 71 | 52 Referred too late or slow management 19 Lost to follow up |
Clinical | ||
Clinical decision not to give chemotherapy or not to discuss the trial | 165 | 72 Frailty/poor performance status 21 Comprehension/language barrier 19 Co-morbidity 16 Inadequate renal function 15 Change in prognosis /condition during primary treatment 11 Change in diagnosis /unclear pathology 6 Complications with primary treatment 3 Suspected poor compliance 2 Depression |
Clinical decision to offer chemotherapy | 84 | |
Prior or concurrent malignancy | 25 | |
Potentially eligible for BLT (n = 253) | ||
Patient refused | 186 | 77 No reason given 61 Did not want chemotherapy 23 Family dissuaded patient 9 Did not want involvement in research 8 Wanted chemotherapy 8 Other reasons |
Entered other treatment trials | 4 | |
Entered Big Lung Trial | 63 |