Results of multivariate linear regression for cytokine concentrations and diagnostic group (ARDS, severe pneumonia, controls) tested pairwise with the extent of the pulmonary infiltrate (bilateral, unilateral, none), the lung injury score, and the SAPS II score
| TNF-α | IL-1β | IL-6 | ||||
| Diagnostic group + extent of pulmonary infiltrates | 0.394 (<0.001) | —2-150 (0.734) | 0.251 (0.029) | —2-150 (0.531) | 0.499 (0.039) | 0.722 (0.003) |
| Diagnostic group + lung injury score | —2-150 (0.469) | 0.410 (<0.001) | —2-150 (0.728) | 0.311 (0.006) | —2-150 | —2-150 |
| Diagnostic group + SAPS II | 0.321 (0.005) | 0.235 (0.037) | 0.244 (0.035) | —2-150 (0.681) | —2-150(0.751) | 0.292 (0.011) |
Results are presented as standardised coefficients (β) with p values in parentheses.
ARDS = acute respiratory distress syndrome; TNF-α = tumour necrosis factor α; IL = interleukin; SAPS = simplified acute physiology score.
↵2-150 Parameter not selected in the stepwise forward linear regression model.