LMP1+ (n=9) | LMP1− (n=20) | p value | |
---|---|---|---|
Mean (range) age (years) | 56 (38–63) | 60 (47–72) | NS |
Sex (M/F) | 6/3 | 16/4 | NS |
Smoking history | 6 | 15 | NS |
Dyspnoea score | 5.8 (4.2) | 4.8 (4.1) | NS |
Clubbing | 6 | 12 | NS |
Radiographic score | 5.5 (1.0) | 4.9 (1.2) | NS |
Laboratory findings at initial examination: | |||
LDH (IU/l) | 251 (101) | 279 (118) | NS |
CRP (mg/dl) | 0.2 (0.2) | 0.5 (0.7) | NS |
Pao 2 (kPa) | 11.0 (0.9) | 11.0 (1.5) | NS |
%VC (%) | 73.6 (33.4) | 79.9 (19.7) | NS |
Bronchoalveolar lavage cells (%) | |||
Macrophages | 91.0 (10.0) | 82.5 (24.2) | NS |
Lymphocytes | 4.7 (7.5) | 13.0 (23.7) | NS |
Neutrophils | 6.6 (3.5) | 5.8 (4.3) | NS |
Eosinophils | 0.5 (1.0) | 1.9 (4.2) | NS |
Mean (range) follow up period (mo) | 42 (12–105) | 41 (3–98) | NS |
Steroid treatment | 6 (67%) | 5 (25%) | <0.05 |
Outcome | |||
Died | 5 (55%) | 5 (25%) | NS |
Cause of death | |||
Respiratory failure | 4 (44%) | 1 (5%) | <0.05 |
Lung cancer | 1 (11%) | 2 (10%) | NS |
Pulmonary infection | 0 | 1 (5%) | NS |
Heart failure | 0 | 1 (5%) | NS |
LDH = lactate dehydrogenase; CRP = C reactive protein; Pao 2 = arterial oxygen tension; VC = vital capacity.
Values are expressed as mean (SD) unless otherwise indicated.