Table 5

Mean (SE) ventilatory responses to hypercapnia and hypoxia after standardising for body surface area and forced vital capacity

RelativesControlsp value
S/BSA (l/min/mmHg/m2)0.84  (0.08)0.77  (0.08)0.6
A/BSA (l/min • mmHg/m2)134 (28.8)133.4 (23.9)1.0
e/Sao 2/BSA (l/min/%/m2)0.70 (0.14)0.54 (0.08)0.4
S/FVC (l/min/mmHg/l)0.57 (0.05)0.55 (0.05)0.8
A/FVC (l/min • mmHg/l)89.0 (15.8)87.8 (13.4)0.9
e/Sao 2/FVC (l/min/%/l)0.46 (0.08)0.38 (0.08)0.5
  • S = slope factor for the ventilatory response to hypercapnia; BSA = body surface area; A = hypoxic ventilatory response;V˙e = minute ventilation; Sao 2= oxygen saturation; FVC = forced vital capacity