Comparison of neutrophil counts and myeloperoxidase (MPO) activity between soluble E-selectin TG mice (n = 10) and non-TG mice (n = 10)
| TG | 0 h | 24 h | 72 h | 168 h | Overall mean difference (95% CI) | ||
| MPO activity | (+) | 3.1 (0.3) | 2.8 (0.2) | 3.2 (0.4) | 2.3 (0.4) | 4.2 (3.0 to 5.4)* | |
| (−) | 3.8 (0.3) | 12.8 (0.5) | 7.2 (0.2) | 4.5 (0.3) | |||
| Neutrophil count | (+) | 28 (2.0) | 32 (1.9) | 32 (1.4) | 46 (1.0) | 136.5 (109 to 164)* | |
| (−) | 34 (2.3) | 248 (3.1) | 230 (3.2) | 168 (4.1) |
Mean neutrophil counts (/cm2) of five sections of lung tissue stained with Giemsa; myeloperoxidase activity (U/ml) was measured at several time points after injection of BLM. Both parameters differed significantly between TG and non-TG mice (*p<0.001).