Summary of reports of methotrexate for sarcoidosis
| Reference | Patients treated | Response | Other drugs | Major organs |
|---|---|---|---|---|
| Lacher16 | 1 | 1 | Prednisone tapered off | Lungs, skin |
| Veien51 | 16 | 12/16 with skin, 3/4 with eye | None | Skin, lungs, eye |
| Fenton52 | 1 | 1 | Prednisone tapered | Nasal, skin |
| Lower23 | 15 | Lungs in 9/15, skin 3/3, liver 2/2 | Prednisone tapered in 9/10 | Lung, liver, skin, |
| Soriano53 | 1 | 1 | Prednisone discontinued | Neurological, Heerfordt’s |
| Webster54 | 3 | 3 | Intralesional corticosteroids | Skin |
| Chittock55 | 1 | 1 | Prednisone tapered | Pleural |
| Henderson56 | 1 | 1 | No | Laryngeal, cutaneous |
| Rajendran57 | 12 | Excellent 7, good 4 | Four good responders on prednisone | Skin |
| Lower32 | 50 | Lung in 17/50, skin in 16/17, eye in 2/2 | Prednisone tapered in 29/33, 16 tapered off | Lungs, skin, eyes |
| Lennarson58 | 1 | 1 | Prednisone tapered | Eye |
| Kaye59 | 5 | 5 | Prednisone tapered in 4 of 4 | Musculoskeletal, liver |
| Agbogu60 | 3 | 1 | Prednisone tapered | Neurological |
| Pia29 | 11 | 11 | Corticosteroids, cyclosporin | Lung, skin, arthritis |
| Gedalia30 | 7 | Complete 5, partial 1 | Prednisone for four weeks only in 6 of 7 | Skin, joints, eye, lung |
| Lower13 | 28 | 17 | Prednisone tapered in all | Neurological |
| Morishita61 | 9 | 5 | Prednisone | Cardiac |