Bone mineral density (g/cm2) of lumbar spine
|
FP400 (n=22) |
BDP800 (n=21) | p value FP-BDP4-150 |
FP750 (n=13) | BDP1500 (n=13) | p value FP-BDP4-150 | |
| Baseline median | 1.26 | 1.14 | 1.25 | 1.14 | ||
| Interquartile range | 1.05–1.33 | 1.08–1.19 | 1.09–1.35 | 1.05–1.19 | ||
| 6 months | ||||||
| Median change | 0.005 | 0.005 | NS | −0.004 | 0.0 | NS |
| Quartile change | −0.004, 0.022 | −0.013, 0.020 | −0.031, 0.019 | −0.011, 0.010 | ||
| 12 months | ||||||
| Median change | 0.020 | −0.003 | 0.02 | 0.005 | −0.005 | NS |
| Quartile change | −0.005, 0.033 | −0.016, 0.009 | −0.023, 0.019 | −0.018, 0.021 | ||
FP400 = fluticasone propionate 400 μg/day (200 μg bd); FP750 = fluticasone propionate 750 μg/day (375 μg bd); BDP800 = beclomethasone dipropionate 800 μg/day (400 μg bd); BDP1500 = beclomethasone dipropionate 1500 μg/day (750 μg bd).
↵4-150 p value FP-BDP = significance derived from Wilcoxon rank sum test (difference between treatments in change from baseline).