Table 4

Distribution of mEPHX, GST M1, and GST T1 genotypes in combination

Frequency of putative slow phenotype for mEPHX4-150
Both slow genotype Others
Control (n = 76)29 (38%)47 (62%)
 COPD (n = 83)23 (28%)60 (72%)
 OR (95% CI)1.00.74 (0.38 to 1.45)
 OR (95% CI), smoking adjusted1.00.70 (0.33 to 1.48)
Frequency of null genotypes in both GSTM1 and T1 genes
Both null genotype Others
Control (n = 76)29 (38%)47 (62%)
 COPD (n = 83)28 (34%)55 (66%)
 OR (95% CI)1.00.83 (0.43 to 1.58)
 OR (95% CI), smoking adjusted1.01.04 (0.51 to 2.12)
Frequency of putative slow phenotype of mEPHX and both null genotype of GST M1 and T14-151
Putative slow phenotype (mEPHX) two null (GST) genotypes Others
Control (n = 76)8 (11%)68 (89%)
 COPD (n = 83)9 (11%)74 (89%)
 OR (95% CI)1.01.03 (0.38 to 2.84)
 OR (95% CI), smoking adjusted1.01.28 (0.44 to 3.67)
  • 4-150 Homozygous mutant genotype in exon3 and homozygous wild type in exon 4 of mEPHX gene.

  • 4-151 p>0.05.