Influence of known risk factors on likelihood of transmission of the IL8–251A allele
| Risk factor | n | T | NT | %T (95% CI) | p value |
|---|---|---|---|---|---|
| All infants | 83 | 69 | 43 | 62 (53 to 71) | 0.014 |
| Infants with no siblings | 26 | 26 | 10 | 72 (58 to 87) | 0.008 |
| Infants with no siblings and excluding those with prematurity | 20 | 22 | 7 | 76 (60 to 91) | 0.005 |
| Infants with no siblings and excluding those with prematurity and those with cardiac disease | 18 | 21 | 6 | 78 (62 to 93) | 0.004 |
n = number of informative probands; T = transmitted; NT = non-transmitted; %T = percentage of –215A alleles transmitted.
The p values, based on Pearson's test statistic, reflect the significance of the deviation of the % transmission from the expected 50%.