Extracellular matrix immunostaining in bronchial biopsy specimens
| Healthy volunteers (n = 8) | Non-steroid treated asthmatics (n = 9) | Steroid treated asthmatics (n = 8) | |
|---|---|---|---|
| Computer assisted image analysis stained area (% of total) | |||
| MMP-9 | 0.38 (0.07–2.21) | 0.16 (0.02–0.48) | 1.12 (0.02–3.54) |
| MMP-3 | 0.0 (0.0–0.39) | 0.004 (0.0–0.39) | 0.17 (0.0–1.49) |
| Rank order analysis of photomicrographs | |||
| MMP-9 | 14 (7–24) | 9 (1–19) | 15 (5–25) |
| MMP-3 | 0 (0–12) | 5 (0–10) | 12 (0–16) |
Values are median (range).