Mean (SD) bone turnover marker levels, vitamin D levels, and parathyroid hormone levels in delta F508 homozygote and non-delta F508 homozygote cystic fibrosis adult patients
| Delta F508 homozygotes (n = 90) | Non-delta F508 homozygotes (n = 57) | p value | |
|---|---|---|---|
| Osteocalcin (ng/ml) | 10.6 (4.2) | 10.0 (3.9) | NS |
| Bone specific alkaline phosphatase (U/l) | 22.5 (11.1) | 18.1 (6.9) | 0.01 |
| Deoxypyridinoline crosslinks (nM/mM creatinine) | 7.9 (5.3) | 6.2 (4.6) | 0.005 |
| 25-hydroxyvitamin D (ng/ml) | 17.2 (9.0) | 22.0 (13.5) | NS |
| 1,25-dihydroxyvitamin D (pg/ml) | 31.5 (11.7) | 32.7 (14.4) | NS |
| Parathyroid hormone (pg/ml) | 27.0 (14.2) | 24.3 (13.6) | NS |