Changes between 1989 and 1995 in respiratory symptoms during the preceding 12 months in subjects with soybean epidemic and non-epidemic asthma (relative risk with 95% CI)
| Symptom | Epidemic subjects (%) | Non-epidemic subjects (%) | Relative risk crude | Relative risk adjusted3-151 |
|---|---|---|---|---|
| Wheeze | ||||
| Improvement3-150 | 15 (20.2) | 15 (19.5) | 1.04 (0.55 to 1.97) | 1.01 (0.53 to 1.93) |
| Worsening3-150 | 16 (53.3) | 16 (72.9) | 0.73 (0.48 to 1.12) | 0.72 (0.47 to 1.10) |
| Attacks of shortness of breath | ||||
| Improvement | 32 (53.4) | 35 (59.4) | 0.90 (0.65 to 1.23) | 0.80 (0.61 to 1.05) |
| Worsening | 9 (20.6) | 7 (17.6) | 1.17 (0.48 to 2.85) | 1.51 (0.63 to 3.59) |
| Tightness in the chest | ||||
| Improvement | 20 (49.9) | 32 (60.3) | 0.83 (0.57 to 1.21) | 0.73 (0.49 to 1.06) |
| Worsening | 17 (26.5) | 14 (30.3) | 0.87 (0.48 to 1.59) | 0.91 (0.48 to 1.71) |
| Woken up by attacks of cough | ||||
| Improvement | 8 (23.5) | 13 (37.0) | 0.63 (0.30 to 1.33) | 0.47 (0.22 to 0.99) |
| Worsening | 20 (28.5) | 16 (25.0) | 1.14 (0.65 to 2.00) | 1.12 (0.64 to 1.95) |
| Woken up by shortness of breath | ||||
| Improvement | 28 (59.5) | 22 (45.8) | 1.30 (0.88 to 1.91) | 1.25 (0.87 to 1.84) |
| Worsening | 12 (21.0) | 9 (17.7) | 1.19 (0.55 to 2.59) | 1.38 (0.63 to 3.06) |
| Attack of asthma | ||||
| Improvement | 24 (57.2) | 30 (61.2) | 0.93 (0.66 to 1.32) | 0.88 (0.64 to 1.21) |
| Worsening | 24 (38.7) | 13 (25.9) | 1.49 (0.85 to 2.61) | 1.65 (0.93 to 2.93) |
| Emergency room visits by asthma | ||||
| Improvement | 12 (52) | 28 (80) | 0.65 (0.42 to 0.99) | 0.63 (0.41 to 0.96) |
| Worsening | 16 (19.8) | 8 (12.5) | 1.58 (0.72 to 3.46) | 1.60 (0.71 to 3.61) |