Table 2

Characteristics of subjects with epidemic and non-epidemic asthma in 1995 (n = 203)

Epidemic asthma
(n = 104)
Non-epidemic asthma
(n = 99)
Mean (SD) age (years)61.6 (15.2)2-150 53.7 (15.6)
Women (%)51.32-150 76.1
Atopy (%)2-153 60.953.7
Geometric mean total IgE (kU/l)106.22-150 59.8
Mean (SD) FEV1 (% predicted)62.7 (26.3)66.8 (23.9)
Bronchial responsiveness (%)2-151 73.078.8
Use of inhaled glucocorticoids (%)65.465.7
Tobacco
Never smokers (%)48.762.1
 Ex-smokers (%)34.622.4
 Current smokers (%)16.715.5
Skin soybean sensitivity (%)2-152 57.82-150 5.6
Serum soybean specific IgE (%)55.12-150 6.0
  • 2-150 p<0.05 for comparison between epidemic and non-epidemic asthmatic subjects.

  • 2-153 Atopy defined as one or more positive skin prick tests to a panel of allergens including house dust, Dermatophagoides pteronyssinus, Dermatophagoides farinae, cat, dog, tree mix, graminaceae mix, weed mix, Aspergillus, andAlternaria.

  • 2-151 92.3% and 94.6% epidemic and non-epidemic asthmatic subjects, respectively, positive to methacholine when performed and 48.3% and 50%, respectively, positive to bronchodilator test.

  • 2-152 Soybean sensitivity by prick to 1/10 glycerinated solution of soybean.