Clinical characteristics of the study population
| Subjects (n = 134) | |
|---|---|
| Mean (SD) age (years) | 34 (11) |
| Sex (F/M) | 61/73 |
| Geometric mean (95% CI) range PC20 (mg/ml) | 1.18 (0.93 to 1.49) |
| Mean (SD) FEV1 (ml) | 3229 (724) |
| Mean (SD) FEV1 (% predicted) | 86 (15) |
| Smoking history: | |
| Current smokers (pack years1-150) | 25 (10) |
| Ex-smokers (pack years1-150) | 30 (13) |
| Never smokers | 79 |
| Medication used during 4 weeks prior for testing: | |
| Beta2 agonist (less than once a day) | 5 |
| Combination of beta2 agonist and anticholinergica (Berodual) | |
| Less than once a day | 76 |
| Regular (once a day or more) | 15 |
| Regular anti-histamine (once a day) | 7 |
| Beclomethasone nose spray | |
| Less than once a day | 1 |
| Regular | 1 |
↵1-150 1 pack year = 365 (days) × 20 (cigarettes) ever smoked.