Promoters | Growth | Inhibitors | Promoters | Migration | Inhibitors | |
---|---|---|---|---|---|---|
EGF/TGFα86 88 | + | + | ||||
Acidic FGF86 88 | + | + | ||||
Basic FGF86 | + | + | ||||
FGF-7/KGF1-150 86 88 91 | + | + | ||||
IL-61-151 86 88 | + | + | + | |||
HGF86 88 | + | + | ||||
IL-21-152 88 135 | + | + | ||||
PDGF86 88 | + | + | ||||
TGFβ1-153 86 88 | + | + | + | |||
IFN-γ1-154 88 135 | + | + | + | |||
IGF-I and II88 87 | + | + |
↵1-150 KGF is pro-migratory for lung alveolar epithelial cells (LAEC) seeded on a fibronectin matrix but not on a neutral gelatin matrix.88 ,135
↵1-151 IL-6 is equivocal factor of LAEC growth and migration but inhibits TGFα- and EGF-induced LAEC migration on gelatin matrix.88
↵1-152 IL-2 is equivocal factor of LAEC migration but promoter when cells have been pre-exposed to IFN-γ.88
↵1-153 Amongst TGFβ isoforms only TGFβ3 is pro-migratory for LAEC.88
↵1-154 IFN-γ is equivocal factor of LAEC migration but inhibits TGFα- and EGF-induced LAEC migration on gelatin matrix.88