Percentage change in bone markers from baseline at 12 months (intention to treat sample)
| FP | BUD | ||
|---|---|---|---|
| Osteocalcin (μg/ml) | n | 24 | 17 |
| Mean (SE) | 16.87 (6.03) | 14.30 (6.40) | |
| p value (within group) | 0.023 | 0.04 | |
| Difference between means (SE) | −3.46 (8.81) | ||
| 95% CI | (−21.27 to 14.36) | ||
| p value (between groups) | 0.70 | ||
| PICP (μg/l) | n | 24 | 17 |
| Mean (SE) | 1.29 (4.70) | 11.16 (8.10) | |
| p value (within group) | 0.79 | 0.19 | |
| Difference between means (SE) | 6.23 (7.69) | ||
| 95% CI | (−9.33 to 21.79) | ||
| p value (between groups) | 0.42 | ||
FP = fluticasone propionate 500 μg twice daily; BUD = budesonide 800 μg twice daily; PICP = procollagen type 1 C-terminal propeptide; SE = standard error; CI = confidence interval.