Percentage change per year in bone mineral density (BMD; g/cm2) from baseline at 12 months (intention to treat sample includes patients given oral steroids during trial)
| FP | BUD | ||
|---|---|---|---|
| Spine | n | 25 | 16 |
| Mean (SE) | 0.49 (0.77) | 1.59 (0.90) | |
| p value (within group) | 0.53 | 0.10 | |
| Difference between means (SE) | 1.07 (1.16) | ||
| 95% CI | (−1.28 to 3.43) | ||
| p value (between groups) | 0.36 | ||
| Femoral neck | n | 25 | 16 |
| Median | −1.61 | 0.15 | |
| Lower quartile | −2.88 | −2.09 | |
| Upper quartile | 0.23 | 2.76 | |
| p value (within group) | 0.043 | 1.00 | |
| p value (between groups) | 0.043 | ||
| Femoral trochanter | n | 25 | 16 |
| Median | 1.77 | 2.95 | |
| Lower quartile | −0.68 | −0.37 | |
| Upper quartile | 5.13 | 5.40 | |
| p value (within group) | 0.067 | 0.21 | |
| p value (between groups) | 0.36 | ||
FP = fluticasone propionate 500 μg twice daily; BUD = budesonide 800 μg twice daily; SE = standard error; CI = confidence interval.