Characteristics of patients with progressive Wegener’s granulomatosis (n = 19)
| Female:male | 8:11 |
|---|---|
| Age (years) | 60 (54–64) |
| Duration of disease (months) | 39 (11–87) |
| ESR (mm/h) | 90 (40–105) |
| C-reactive protein (mg/dl) | 11.3 (2.1–15.8) |
| Disease extent index (DEI score) | 7 (3–11) |
| Cumulative organ involvement (n) | |
| Upper respiratory tract | 19 |
| Kidney | 14 |
| Eye | 12 |
| Arthritis | 16 |
| Polyneuropathy | 7 |
| Central nervous system | 2 |
| Skin | 4 |
| Heart | 3 |
| Gastrointestinal | 2 |
| VCIN (% predicted) | 94 (78–106) |
| FEV1/VCIN (%) | 71 (62–78) |
| Tlco/Va (% predicted) | 115 (95–120) |
VCIN = inspiratory vital capacity; FEV1 = forced expiratory volume in one second; Tlco = carbon monoxide transfer factor; Va = alveolar volume.
Values are median (interquartile range).