Immunophenotyping of peripheral blood (PB) monocytes and alveolar macrophages (AM)
| PB monocytes | AM | PB monocytes vs AM | |
|---|---|---|---|
| CD11a | 51.9 (8.0) | 31.8 (4.0) | p<0.0001 |
| CD11b | 268.1 (140.2) | 80.5 (29.0) | p<0.0001 |
| CD11c | 16.0 (5.0) | 25.3 (5.4) | p<0.0001 |
| CD14 | 57.8 (18.8) | 4.8 (1.3) | p<0.0001 |
| CD16 | 29.9 (9.2) | 51.1 (13.8) | p<0.0001 |
| CD54 | 25.7 (7.2) | 70.1 (33.8) | p<0.0001 |
| CD71 | 1.8 (1.4) | 55.2 (29.2) | p<0.0001 |
| CD80 | 2.0 (2.6) | 5.0 (6.9) | p<0.0001 |
| CD86 | 0.7 (0.6) | 4.3 (2.1) | p<0.01 |
| HLA-DR | 59.9 (12.9) | 401.1 (78.8) | p<0.0001 |
Values depict mean (SD) fluorescence intensities and p values for comparisons between cell subsets.
Significant differences between patient groups (A/IA = active/inactive disease): CD11a PB monocytes A/IA 53.9/46.9 (p<0.05); CD11a AM A/IA 33.2/28.1 (p<0.05).