Recommended drug regimens for adults and children
| Initial phase | Continuation phase | Total months | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Drugs | Months | Drugs | Months | ||||||
| Respiratory and non-respiratory | HRZ(E) | 2 | HR | 4 | 6 | ||||
| Meningitis/CNS | HRZ(E) | 2 | HR | 10 | 12 | ||||
| Chemoprophylaxis | H | 6 | 6 | ||||||
| HR | 3 | 3 | |||||||
| For isoniazid resistant organisms | R | 6 | 6 | ||||||
R = rifampicin; H = isoniazid; Z = pyrazinamide; E = ethambutol.
(E) Ethambutol may be omitted in previously untreated white patients who are known to be HIV negative or thought likely to be on negative risk assessment and not contacts of a case of known drug resistance.