Table 2

Summary of linkage studies (as of May 1998)

ChromosomePhenotypesOxfordCSGAOther (references)Candidates
4IgE, BHR+
5IgE, BHR+++12-14 IL-4,5,9,13, β2AR
6Eos+MHC, TNFα
7BHR++
11Atopy, asthma+++15 16 FcεR1β, CC16
12Asthma+17 IFN-γ
13Atopy+
14Atopy++TCR-α
16Atopy, IgE, asthma++IL-4Rα
  • Only chromosomal regions where at least one study has reported an LOD of 3 (or equivalent) are shown. Eos = eosinophil count.