Factor | Mean difference from reference group or regression coefficient | 95% confidence interval | p value |
---|---|---|---|
Total IgE (log10kU/l) | −0.13 | −0.34 to 0.08 | 0.23 |
Specific IgE to: | |||
Cat | −0.59 | −1.09 to −0.08 | 0.02 |
D pteronyssinus (just positive) | −0.72 | −1.07 to −0.37 | <0.001 |
per 10 kU/l increase above 0.35 | −0.22 | −0.39 to −0.05 | 0.01 |
Timothy grass | −0.50 | −0.84 to −0.15 | 0.005 |
Cladosporium | −1.44 | −2.24 to −0.64 | <0.001 |
Birch | 0.49 | −0.08 to 1.06 | 0.09 |
(FEV1 - predicted)/RSD | 0.37 | 0.21 to 0.53 | <0.001 |
FEV1%FVC | 0.09 | 0.07 to 0.12 | <0.001 |
Per 10 cm of height | 0.36 | 0.16 to 0.55 | <0.001 |
Females - males | −0.75 | −1.12 to −0.38 | <0.001 |
Centre: | <0.001 | ||
Ipswich-Cambridge | 0.55 | 0.20 to 0.89 | |
Norwich-Cambridge | 1.11 | 0.76 to 1.46 | |
Parental atopy | −0.23 | −0.50 to 0.04 | 0.10 |
Season of testing: | 0.04 | ||
Spring-winter | 0.31 | −0.08 to 0.69 | |
Summer-winter | 0.02 | −0.35 to 0.39 | |
Autumn-winter | −0.22 | −0.68 to 0.23 | |
Number of siblings | 0.08 | ||
1 - none | 0.09 | −0.39 to 0.57 | |
2 - none | 0.44 | −0.04 to 0.92 | |
3 - none | 0.13 | −0.40 to 0.66 | |
4 - none | 0.47 | −0.06 to 0.99 | |
Smoking: difference at age 20 from Non-smoker | |||
Ex-smoker | 0.54 | −0.24 to 1.32 | 0.18 |
Current smoker | 0.74 | 0.08 to 1.40 | 0.03 |
Age/smoking: increase per 10 years of age in | |||
Non-smokers | 0.53 | 0.27 to 0.80 | <0.001 |
Ex-smokers | 0.10 | −0.31 to 0.51 | 0.64 |
Smokers | −0.16 | −0.54 to 0.21 | 0.39 |
Total variation explained after adjusting for centre 33.3%
RSD = residual standard deviation in prediction model for FEV1.