Table 6

Final multiple regression model of relation of slope to specific IgE and other factors for 757 subjects

FactorMean difference from reference group or regression coefficient95% confidence intervalp value
Total IgE (log10kU/l)−0.13−0.34 to 0.080.23
Specific IgE to:
 Cat−0.59−1.09 to −0.080.02
 D pteronyssinus (just positive)−0.72−1.07 to −0.37<0.001
 per 10 kU/l increase above 0.35−0.22−0.39 to −0.050.01
 Timothy grass−0.50−0.84 to −0.150.005
 Cladosporium −1.44−2.24 to −0.64<0.001
 Birch0.49−0.08 to 1.060.09
(FEV1 - predicted)/RSD0.37 0.21 to 0.53<0.001
FEV1%FVC0.09 0.07 to 0.12<0.001
Per 10 cm of height0.36 0.16 to 0.55<0.001
Females - males−0.75−1.12 to −0.38<0.001
Centre:<0.001
 Ipswich-Cambridge0.55 0.20 to 0.89
 Norwich-Cambridge1.11 0.76 to 1.46
Parental atopy−0.23−0.50 to 0.040.10
Season of testing:0.04
 Spring-winter0.31−0.08 to 0.69
 Summer-winter0.02−0.35 to 0.39
 Autumn-winter−0.22−0.68 to 0.23
Number of siblings0.08
 1 - none0.09−0.39 to 0.57
 2 - none0.44−0.04 to 0.92
 3 - none0.13−0.40 to 0.66
 4 - none0.47−0.06 to 0.99
Smoking: difference at age 20 from Non-smoker
 Ex-smoker0.54−0.24 to 1.320.18
 Current smoker0.74 0.08 to 1.400.03
Age/smoking: increase per 10 years of age in
 Non-smokers0.53 0.27 to 0.80<0.001
 Ex-smokers0.10−0.31 to 0.510.64
 Smokers−0.16−0.54 to 0.210.39
  • Total variation explained after adjusting for centre 33.3%

  • RSD = residual standard deviation in prediction model for FEV1.