Response and selected characteristics of responders to stage II
| Selected | 1864 | |
|---|---|---|
| Responded to stage II (%)1-1 | 1198 (64.3) | |
| Methacholine challenge1-2 | Yes | No1-3 |
| n (%) | 856 (71.5) | 342 |
| Mean (SD) age | 33.5 (6.8) | 33.1 (7.0) |
| Female (% of n) | 449 (52.5) | 235 (68.7) |
| Parental atopy (% of n) | 270 (31.5) | 90 (26.3) |
| Non smokers (% of n) | 447 (52.2) | 175 (51.2) |
| Ex smokers (% of n) | 186 (21.7) | 65 (19.0) |
| Current smokers (% of n) | 220 (25.7) | 102 (29.8) |
| Data available (n′) | 856 | 1681-4 |
| Recent RI (% of n′) | 30 (3.5) | 6 (3.6) |
| Recent medication (% of n′) | 18 (2.1) | 18 (10.7) |
| Mean (SD) FEV1 (% pred) | 105.6 (11.5) | 98.4 (19.9) |
| Mean (SD) FEV1/FVC | 82.9 (6.2) | 81.1 (10.1) |
↵1-1 Responded to at least the questions on smoking.
↵1-2 Valid slope, therefore at least two doses of methacholine.
↵1-3 Subjects who declined lung function or were ineligible for challenge or unable to proceed.
↵1-4 Subjects who had baseline lung function but were ineligible for challenge, declined further participation, or were unable to proceed.
RI = respiratory infection; FEV1 = forced expiratory volume in one second; FVC = forced vital capacity.