Table 6

Symptoms and bronchodilator use. Within treatment comparisons using data for weeks 21–24 as baseline were also used for the analysis of washout effects

		Placebo	Salbutamol	Salmeterol
Day time
Wheeze/tightness (% days with score = 0)	Run in	61.3	62.0	64.4
	Weeks 0–24	63.6	72.3^6-150	79.8^6-151
	Weeks 21–24	64.3	72.4^6-150	80.1^6-151
	Washout 0–4	65.8	62.3	60.3^6-159
Rescue bronchodilator (% days with 0 puffs)	Run in	54.6	53.4	57.9
	Weeks 0–24	59.8	72.5^6-150	79.3^6-151
	Weeks 21–24	60.7	73.7^6-150	79.3^6-151
	Washout 0–4	61.1	59.3	58.7
Night-time
Wheeze/tightness (% nights with score = 0)	Run in	75.5	76.0	78.2
	Weeks 0–24	75.6	77.8	87.7^6-151
	Weeks 21–24	76.7	78.4	89.4^6-151
	Washout 0–4	79.0	76.5	75.4^6-152
Rescue bronchodilator (% nights with 0 puffs)	Run in	79.3	76.8	78.0
	Weeks 0–24	77.8	86.5^6-150	92.2^6-151
	Weeks 21–24	78.3	88.1^6-150	92.7^6-151
	Washout 0–4	80.2	80.6	80.8

↵6-150 p<0.05, salbutamol better than placebo.
↵6-151 p<0.001, salmeterol better than placebo
↵6-159 p=0.005, salmeterol worse than placebo
↵6-152 p=0.03, salmeterol worse than placebo