Withdrawals during the study
| Reason for withdrawal | Placebo | Salbutamol | Salmeterol |
|---|---|---|---|
| Poor asthma control | 1 (1) | 0 | 2 (1) |
| Adverse events related to study treatment | 1 | 8 (5)* | 0 |
| Adverse events unrelated to study treatment | 2 | 2 | 2 (1) |
| Poor compliance/social reasons | 6 | 5 | 3 |
| Pregnancy/inadequate contraception | 2 | 1 | 0 |
| Total (n = 35) | 12 | 16 | 7 |
Figures in brackets indicate the number of patients who continued to the next treatment period if the adverse event occurred during treatment periods 1 or 2. *In all cases withdrawal was on account of tremor and/or palpitations.