Table 2

Crude and adjusted* risk (incidence rate ratio, IRR) of incident hospitalisations for chronic obstructive pulmonary disease

Crude IRR (95% CI)Adjusted* IRR (95% CI)
Modified GOLD stage
 Normal1.01.0
 Restricted4.3 (3.3 to 5.5)4.7 (3.7 to 6.1)
 GOLD 02.3 (1.8 to 2.9)2.1 (1.6 to 2.6)
 GOLD 13.9 (3.1 to 4.9)3.2 (2.6 to 4.0)
 GOLD 28.6 (6.9 to 10.7)8.0 (6.4 to 10.0)
 GOLD 3 or 422.5 (17.3 to 29.4)25.5 (19.5 to 33.4)
  • * Zero-inflated negative binomial regression adjusted for age, gender, education, smoking, physical activity, diabetes, heart disease and cohort (Atherosclerosis Risk in Communities Study/Cardiovascular Health Study).

  • Modified Global Initiative on Obstructive Lung Disease (GOLD): normal (no lung disease), restricted (FEV1/FVC ≥0.70 and FVC <80% predicted), GOLD stage 0 (presence of respiratory symptoms in the absence of any lung function abnormality), GOLD stage 1 (FEV1/FVC <0.70 and FEV1 ≥80%), GOLD stage 2 (FEV1/FVC <0.70 and FEV1 ≥50% to <80% predicted) and GOLD stages 3 or 4 (FEV1/FVC <0.70 and FEV1 <50% predicted).