Concentration of β-methacholine (μg/kg) producing 20% increase above baseline in airway occlusion
| Exposure | |||||
|---|---|---|---|---|---|
| Saline | Ovalbumin 2 wk | Ovalbumin 4 wk | Ovalbumin 6 wk | Ovalbumin 8 wk | |
| Non-immunised mice | 174.0 | 243.0 | 36.7 | 39.6 | 38.8 |
| Boosted mice | 138.2 | 56.3 | 22.0 | 43.2 | 29.3 |
Calculated from the fourth order polynomial curve fitted to the dose-response data.