RT Journal Article
SR Electronic
T1 Association between asthma and lung function in adolescents born very preterm: results of the EPIPAGE cohort study
JF Thorax
JO Thorax
FD BMJ Publishing Group Ltd and British Thoracic Society
SP thoraxjnl-2017-211115
DO 10.1136/thoraxjnl-2017-211115
A1 Alice Hadchouel
A1 Jessica Rousseau
A1 Jean-Christophe Rozé
A1 Catherine Arnaud
A1 Adèle Bellino
A1 Laure Couderc
A1 Stéphane Marret
A1 Marie Mittaine
A1 Didier Pinquier
A1 Marie Verstraete
A1 Pierre-Yves Ancel
A1 Christophe Delacourt
A1 ,
YR 2018
UL http://thorax.bmj.com/content/early/2018/03/30/thoraxjnl-2017-211115.abstract
AB Prematurity and bronchopulmonary dysplasia (BPD) affect long-term lung function. We studied the respiratory outcome of adolescents born very preterm and controls from the Etude EPIdémiologique sur les Petits Ages Gestationnels cohort and analysed their current lung function in relation to asthma symptoms (categorised in three age groups) from birth. In models including BPD, asthma at each age and confounding factors in the preterm group, BPD and preschool wheeze were the only independent variables associated with FEV1. Preschool wheeze is an independent factor associated with FEV1 impairment in adolescents born very preterm. These results highlight the need for optimal management of early respiratory symptoms in preterm-born infants.Trial registration number Results, NCT01424553.