RT Journal Article SR Electronic T1 Olfactory dysfunction is worse in primary ciliary dyskinesia compared with other causes of chronic sinusitis in children JF Thorax JO Thorax FD BMJ Publishing Group Ltd and British Thoracic Society SP thoraxjnl-2017-210661 DO 10.1136/thoraxjnl-2017-210661 A1 Massimo Pifferi A1 Andrew Bush A1 Michele Rizzo A1 Alessandro Tonacci A1 Maria Di Cicco A1 Martina Piras A1 Fabrizio Maggi A1 Giulia Paiola A1 Angela Michelucci A1 Angela Cangiotti A1 Diego Peroni A1 Davide Caramella A1 Attilio L Boner YR 2018 UL http://thorax.bmj.com/content/early/2018/02/27/thoraxjnl-2017-210661.abstract AB Cilia have multiple functions including olfaction. We hypothesised that olfactory function could be impaired in primary ciliary dyskinesia (PCD). Olfaction, nasal nitric oxide (nNO) and sinus CT were assessed in patients with PCD and non-PCD sinus disease, and healthy controls (no CT scan). PCD and non-PCD patients had similar severity of sinus disease. Despite this, defective olfaction was more common in patients with PCD (P<0.0001) and more severe in patients with PCD with major Transmission Electron Microscopy (TEM) abnormalities. Only in classical PCD did olfaction inversely correlate with sinusitis and nNO. We speculate that defective olfaction in PCD is primary in nature.