RT Journal Article
SR Electronic
T1 Validity, responsiveness and minimum clinically important difference of the incremental shuttle walk in idiopathic pulmonary fibrosis: a prospective study
JF Thorax
JO Thorax
FD BMJ Publishing Group Ltd and British Thoracic Society
SP thoraxjnl-2017-210589
DO 10.1136/thoraxjnl-2017-210589
A1 Claire M Nolan
A1 Veronica Delogu
A1 Matthew Maddocks
A1 Suhani Patel
A1 Ruth E Barker
A1 Sarah E Jones
A1 Samantha S C Kon
A1 Toby M Maher
A1 Paul Cullinan
A1 William D-C Man
YR 2017
UL http://thorax.bmj.com/content/early/2017/09/07/thoraxjnl-2017-210589.abstract
AB The incremental shuttle walk (ISW) is well validated in COPD but limited psychometric data restrict its use in idiopathic pulmonary fibrosis (IPF). Study 1: 50 patients performed the ISW and 6 min walk test (6MWT). Study 2: 72 patients completed the ISW before and after pulmonary rehabilitation (PR). The ISW correlated strongly with 6MWT distance (r=0.81,p<0.0001). Mean (95% confidence interval) improvement in ISW with PR was 54 (38 to 70) m with an effect size of 0.29. Distribution-based and anchor-based minimum clinically important difference (MCID) estimates ranged from 31 to 46 m. The ISW is valid and responsive in IPF, with an anchor-based MCID estimate similar to that observed in chronic obstructive pulmonary disease.Trial registration number Pre-results; NCT02530736, NCT02436278.