PT  - JOURNAL ARTICLE
AU  - D J Lewis
AU  - P R Jakins
TI  - Effect of tobacco smoke exposure on rat tracheal submucosal glands: an ultrastructural study.
AID  - 10.1136/thx.36.8.622
DP  - 1981 Aug 01
TA  - Thorax
PG  - 622--624
VI  - 36
IP  - 8
4099  - http://thorax.bmj.com/content/36/8/622.short
4100  - http://thorax.bmj.com/content/36/8/622.full
SO  - Thorax1981 Aug 01; 36
AB  - The ultrastructural appearance of rat tracheal submucosal glands after exposure to tobacco smoke for up to two years is described. Within the mucous cells many of the rough endoplasmic reticulum cisternae were grossly dilated with an accumulation of amorphous, electron-lucent material. The Golgi zones were prominent, and the secretion granules often contained dense cores, and appeared to have coalesced. Histochemically, increased amounts of sulphated mucus were present in exposed rats. Serous, ciliated, and myoepithelial cells were unaffected by smoke exposure.