Prosthetic hip-joint infection associated with a penicillin-tolerant group B streptococcus

J Infect. 1992 Jul;25(1):77-81. doi: 10.1016/0163-4453(92)93609-t.

Abstract

We report a case of prosthetic hip-joint infection with Streptococcus agalactiae (Lancefield group B streptococcus). The infection recurred after 3 months' treatment with amoxycillin. On further investigation, the isolate was found to be amoxycillin-tolerant. Addition of gentamicin abolished tolerance in vitro and the patient has remained asymptomatic since receiving a 10-day course of amoxycillin and gentamicin followed by amoxycillin alone.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Amoxicillin / therapeutic use*
  • Drug Therapy, Combination / therapeutic use
  • Drug Tolerance
  • Gentamicins / therapeutic use*
  • Hip Prosthesis / adverse effects*
  • Humans
  • Male
  • Prosthesis-Related Infections / drug therapy
  • Prosthesis-Related Infections / microbiology*
  • Streptococcal Infections / drug therapy
  • Streptococcal Infections / microbiology*
  • Streptococcus agalactiae*
  • United Kingdom

Substances

  • Gentamicins
  • Amoxicillin