Regulation and function of somatostatin receptors

J Neurochem. 2004 Jun;89(5):1057-91. doi: 10.1111/j.1471-4159.2004.02402.x.

Abstract

This review summarizes the latest advances that have been made to elucidate the somatostatinergic system in respect to somatostatin receptor evolution, the development of receptor agonists/antagonists, receptor regulation, signal transduction, effects on cell proliferation, receptor-receptor or receptor-protein interactions and receptor function.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cell Division / physiology
  • Central Nervous System / metabolism
  • Gastrointestinal Tract / metabolism
  • Humans
  • Ligands
  • Receptors, Somatostatin / drug effects
  • Receptors, Somatostatin / metabolism
  • Receptors, Somatostatin / physiology*
  • Signal Transduction / physiology*
  • Somatostatin / metabolism

Substances

  • Ligands
  • Receptors, Somatostatin
  • Somatostatin