Social and psychosocial influences on inflammatory markers and vascular function in civil servants (the Whitehall II study)

Am J Cardiol. 2003 Oct 15;92(8):984-7. doi: 10.1016/s0002-9149(03)00985-8.

Abstract

Social position and psychosocial factors are associated with coronary disease, but the underlying pathophysiologic mechanisms remain unclear. In a sample of 283 nonsmokers, we found that social position was inversely associated with interleukin-6 and C-reactive protein and that participants with mild depression had impaired endothelial function.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Blood Glucose / analysis
  • Body Constitution
  • C-Reactive Protein / analysis*
  • Coronary Disease / epidemiology*
  • Coronary Disease / psychology
  • Depression / complications
  • Employment*
  • Fasting
  • Female
  • Humans
  • Insulin / analysis
  • Interleukin-6 / analysis*
  • Male
  • Middle Aged
  • Social Class*
  • Surveys and Questionnaires
  • Triglycerides / analysis
  • United Kingdom / epidemiology

Substances

  • Blood Glucose
  • Insulin
  • Interleukin-6
  • Triglycerides
  • C-Reactive Protein