Non-specific effects of anti-sense oligonucleotides on alpha-1-antitrypsin expression in Cos cells transfected with alpha-1-antitrypsin cDNA constructs

Biochem Soc Trans. 1992 Nov;20(4):319S. doi: 10.1042/bst020319s.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Base Sequence
  • Cell Line
  • DNA / genetics*
  • Enzyme-Linked Immunosorbent Assay
  • Gene Expression / drug effects
  • Hydroxymethylbilane Synthase / metabolism
  • Molecular Sequence Data
  • Oligonucleotides, Antisense / pharmacology*
  • RNA / isolation & purification
  • Transfection / drug effects
  • alpha 1-Antitrypsin / biosynthesis*
  • alpha 1-Antitrypsin / genetics

Substances

  • Oligonucleotides, Antisense
  • alpha 1-Antitrypsin
  • RNA
  • DNA
  • Hydroxymethylbilane Synthase