Abstract
High-dose inhaled corticosteroids, greater than 400 mcg per day of beclomethasone dipropionate or equivalent, can cause adrenal insufficiency, but a hypoglycemic crisis has not been reported with the use of nebulized corticosteroids. We describe a 21-month-old asthmatic boy who had a hypoglycemic seizure during a proven acute adrenal crisis secondary to high-dose nebulized budesonide treatment.
Copyright 2002 Wiley-Liss, Inc.
MeSH terms
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Administration, Inhalation
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Adrenal Cortex / drug effects
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Adrenal Cortex Hormones / adverse effects*
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Anti-Inflammatory Agents / adverse effects*
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Asthma / blood
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Asthma / complications*
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Asthma / drug therapy
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Bronchodilator Agents / adverse effects*
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Budesonide / adverse effects*
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Humans
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Hydrocortisone / therapeutic use
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Hypoglycemia / blood
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Hypoglycemia / etiology*
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Infant
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Male
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Nebulizers and Vaporizers
Substances
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Adrenal Cortex Hormones
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Anti-Inflammatory Agents
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Bronchodilator Agents
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Budesonide
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Hydrocortisone